- Earl R. Crouch, Jr., M.D., F.A.C.S. - Chairman, Board of Directors
- Patricia B. Williams, Ph.D., F.C.P. - President
- John D. Sheppard, Jr., M.D., M.M.Sc. - Chief Operating Officer
- Frank A. Lattanzio, Jr., Ph.D. - Vice-President for Research
- Robert L. McKown, Ph.D., - Vice-President, Biomanufacturing
- Sandeep S. Samudre, Ph.D., M.P.H. - Director of Research Operations
- Paul S. Williams - Chief Financial Officer
- Donald C. Holmes - Secretary and Legal Counsel
Earl R. Crouch, Jr., M.D., F.A.C.S.
Dr. Crouch is one of the founding members of EyeRx Research, Inc. He has 20 years experience in ophthalmic research, particularly in the area of the treatment of traumatic hyphema. He has authored over 100 peer review abstracts, journal articles, and chapters.
In addition to his work with EyeRx, Dr. Crouch is Professor and Chairman of the Department of Ophthalmology and Associate Professor of Pediatrics at Eastern Virginia Medical School. In 1988, he received the Honor Award from the American Academy of Ophthalmology. In 1991 he was presented with the Honor Award from the American Association of Pediatric Ophthalmology and Strabismus. In 1992, Dr. Crouch was awarded Outstanding Faculty Member at Eastern Virginia Medical School. In 2010, he received the Senior Honor Award from the American Academy of Ophthalmology.
Dr. Crouch is journal reviewer for three peer-reviewed journals--Ophthalmology, Archives of Ophthalmology, Journal of Pediatric Ophthalmology and Strabismus, and American Journal of Ophthalmology. Dr. Crouch serves on the Professional Information Committee of the American Association of Pediatric Ophthalmology and Strabismus.
Dr. Crouch received his medical degree from the Medical College of Virginia and remained at MCV for his internship. Thereafter, he spent 2 years with the Indian Health Service of the U.S. Public Health Service in Tahlequa, Oklahoma. He completed his ophthalmology residency at the University of Illinois Eye & Ear Infirmary, where he received the award for Most Outstanding Ophthalmic Research. Dr. Crouch then completed fellowship in pediatric ophthalmology and strabismus at Children's Hospital National Medical Center, George Washington University, Washington, DC.
Patricia B. Williams, Ph.D., F.C.P.
Dr. Williams, President, is one of the founding members of EyeRx Research, Inc. With over thirty years experience in both preclinical and clinical pharmacology, she has focuses on the development of safe and efficacious treatments for blinding eye disease. In 1990, she was named a Fellow of the American College of Clinical Pharmacology in recognition of her contributions to the field.
In the late 1980's she teamed with Earl Crouch, Jr. and Dr. John Sheppard to tackle the problem regarding efficacious drugs that are not routinely used due to disabling adverse effects. Their novel approach resulted in products that are equally efficacious and remarkably free of the disabling adverse effects. Drs. Williams, Crouch and Sheppard have been awarded five patents for this work.
In the development process for these products she has been instrumental in interfacing with the FDA, developing manufacturing procedures, participating in the design, conduct and evaluation of clinical trials. Most importantly, she has conducted preclinical trials to expand the clinical indications for these products and related products.
Dr. Williams is author of over 50 publications and a frequent guest speaker at national and international conferences. She serves as consultant to the FDA, NASA and the pharmaceutical industry and serves on an NIH Study Section to evaluate proposals for NIH funding. As a member of VABio (Virginia Biotechnology Association) Board of Directors, she actively promotes the biotechnology industry. For the Commonwealth of Virginia's Center for Innovative Technology she speaks at conferences for early stage biotech entrepreneurs.
In addition to her work with EyeRx Research, she is also Director of the Thomas R. Lee Center for Ocular Pharmacology at the Eastern Virginia Medical School and Professor of Pharmacology and Ophthalmology at EVMS and adjunct professor of chemistry at Old Dominion University. She was graduated from the University of Michigan with a BS in pharmacy and with a PhD in pharmacology from the Medical College of Virginia, Virginia Commonwealth University.
John D. Sheppard, Jr., M.D., M.M.Sc.
Dr. Sheppard, COO, is a founder of EyeRx Research, Inc. As a nationally recognized expert in the diagnosis and treatment of ophthalmologic disease coupled with his training in immunology and preclinical science, his expertise provides a broad base for development of ophthalmologic drugs and devices. In 1995 the American Academy of Ophthalmology presented him with the Honor Award. By peer review he has been named one of the Best Doctors in America, in Virginia and in Norfolk. Dr. Sheppard served as an Associate Examiner for the American Board of Ophthalmology for 7 years and is now a Mentor examiner.
He has participated as principal investigator in over 45 clinical research trials for major pharmaceutical companies and the FDA. Dr. Sheppard serves on the medical advisory boards for several companies. He has authored over 100 peer review abstracts, journal articles, and chapters. An acclaimed speaker, he has presented over 400 invited lectures and visiting professorships worldwide. Dr. Sheppard is at the forefront of the electronic publishing age as uveitis section editor for eMedicine.com as well as an editorial board member for EyeNet, by the AAO.
In 1989, Dr. Sheppard joined Virginia Eye Consultants and is an Associate Professor of Ophthalmology, Microbiology, and Immunology faculty at Eastern Virginia Medical School. In addition, he serves as Director of the Ophthalmology Residency Program at EVMS. As Clinical Director of the Thomas R. Lee Center for Ocular Pharmacology, he not only coordinates clinical trials, but is also instrumental in bringing preclinical studies into clinical practice. During a period of major expansion, he was Chairman of the Board of the Lions Eye Bank of Eastern Virginia.
Dr. Sheppard received a Masters degree in Medical Science and an MD from Brown University on a full Armed Forces Health Professions Scholarship. After an internship in pediatrics at the University of Virginia, he spent four years with the U.S. Navy as 6th Fleet Medical Officer and Chief of Family Practice. He completed his Ophthalmology residency at the University of Pittsburgh Eye and Ear Institute and a 30 month fellowship in corneal diseases, uveitis, third world blindness, and ocular immunology at the Proctor Research Foundation at the University of California, San Francisco.
Frank A. Lattanzio, Jr., Ph.D.
Dr. Lattanzio joined EyeRx Research, Inc. in 2000 as Vice-President of Research. Complementing his expertise in a wide variety of pharmacologic techniques, ranging from studies at the molecular level to integrated systems biology of animal models of disease, is his extensive experience with biomedical instrumentation. He is a leader in the adaptation of confocal microscopy for real time observations in both patients and in animal models of ocular disease.
Dr. Lattanzio is sought out as a consultant for bioinstrumentation application and design by companies including Harvard Apparatus, Radnoti Glass Technologies and IITC, as well as by university and medical schools. For over 15 years, he has created devices and training manuals for in vivo and in vitro pharmacology and physiology that are used in medical schools, research and pharmaceutical laboratories internationally. Examples include isolated organs and tissue baths, pressure transducers and other biomedical sensors and in vitro and in vivo fluorometers. He has also trained researchers in Europe, Japan, China and the United States.
Dr. Lattanzio shares a patent for a class of novel compounds under development for use in glaucoma and other ocular and cardiac diseases. He has written successful SBIR proposals, as well as traditional research grants. In 1992-6 he was a member of a NASA shuttle project for shuttle mission STS-65. He has published in peer reviewed scientific journals, written sales and technical catalogs and presented at scientific symposia and meetings including 3 Gordon Conferences, the American Heart Association, Biophysics Society, Experimental Biology and Association for Research in Vision and Ophthalmology.
Dr. Lattanzio is Assistant Professor of Pharmacology and Ophthalmology at Eastern Virginia Medical School and Director of Basic Science Research at the Thomas R. Lee Center for Ocular Pharmacology. He holds a doctorate in Pharmacology from the University of Miami and completed postdoctoral training in Medicine and Physiology at the University of Texas Health Science Center at Dallas. Dr. Lattanzio also served on the faculties of the University of Miami, University of Texas Southwestern Medical School, University of Nevada-Reno, and Old Dominion University.
Robert L. McKown, Ph.D.
Robert McKown is a Professor in the Department of Integrated Science and Technology at James Madison University. Trained in Molecular Biology and Biochemistry at the University of California Irvine and Molecular Genetics at the University of California San Francisco, Bob has seven years experience in the biotechnology industry working on the development and production of recombinant proteins. He is the originator of the Biotechnology B.S. Program at JMU and Director of the JMU Biomanufacturing Laboratory which focuses on the development and production of human therapeutic and diagnostic products. Bob McKown serves on a number of business and educational boards that include the Virginia Biotechnology Association, the Chesapeake Bioscience Education Foundation and the Biotechnology Training Program at the University of Virginia.